posted in <<Brain Plasticity News > Fibromyalgia News > NEWS

Neurontin and Lyrica are a Death Sentence for New Brain Synapses


Byron J. Richards, CCN reported earlier this month that the popular Fibromyalgia drug Lyrica and its former less potent version Neurontin have both been shown to “block the formation of new brain synapses, drastically reducing the potential for rejuvenating brain plasticity.”

Neurontin was originally produced for epilepsy but was illegally marketed for off-label use by pharmaceutical company Warner-Lambert, the former owner of the drug, who was later fined 430 million dollars.

Lyrica is owned by pharmaceutical giant Pfizer, and was approved by the FDA for pain management including the treatment of fibromyalgia. It, too, was illegally marketed for off-label use and Pfizer lost a $2.3 billion settlement.

Richards writes:

Even though the marketing of these drugs has been heavily fined, they continue to rack up billions in sales from the off-label uses. Doctors use them for all manner of nerve issues because they are good at suppressing symptoms. However, such uses can no longer be justified because the actual mechanism of the drugs is finally understood and they are creating a significant long-term reduction in nerve health.

The researchers in the above study try to downplay the serious nature of the drugs by saying “adult neurons don’t form many new synapses.” That is simply not true. The new science is showing that brain health during aging relies on the formation of new synapses. Even these researchers managed to question the common use of these medications in pregnant women. How is a fetus supposed to make new nerve cells when the mother is taking a drug that blocks them?

These are the kind of situations the FDA should be all over. As usual, the FDA is sitting around pondering a suicide warning for Lyrica while its off-label uses include bi-polar disorder and migraine headaches. The FDA is likely to twiddle its thumbs for the next decade on the brain damage issue. Consumer beware.

Recently here at Planet Thrive, we’ve been publishing articles on the use of brain plasticity to help ameliorate the symptoms of fibromyalgia. What a pity that those who are turning to pharmaceuticals to manage their pain might be reducing their chances for a non-invasive lasting remedy in the process. read the full article

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posted by earthwalker on October 29, 2009 | tags: , , , , , ,


  • Brain Training Advocate

    October 30, 2009 at 4:49 am

    This is unbelievable. How on earth can these companies get away with this? Thanks for the report.


  • earthwalker

    October 31, 2009 at 11:51 am

    It is unbelievable but it is the truth in our country. Our whole country is based on a structure that supports drug companies in doing this. Companies are not required to do extensive long-term safety studies, or if they do, results are allowed to be biased, companies do not have to disclose full ingredients, and are given tax incentives and subsidies to help them poison our land and citizens.

    At least that’s the view from where I sit, poisoned from chemicals and now a virtual prisoner in my home. Thanks to the pervasive lack of regulation on toxic chemicals in our country.

  • Jason Aaron Childs

    June 6, 2016 at 3:01 am

    I love neurontin. It always pulls me through when I run out of my prescription medication, Norco. It also helps keep me from going through the nasty drug withdrawal symptoms. It is basically a miracle medication to me. Also, stating the obvious, it does help with the pain.

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