Holmes Mercury Chelation Protocol

by | Aug 20, 2009 | Autism Spectrum Disorders, Heavy Metal Poisoning, TREATMENTS | 2 comments

developed by: Amy S. Holmes, MD


Holmes Mercury Chelation ProtocolAmy S. Holmes, MD, known as “Dr. Amy” to her patients, is a physician whose son developed autism, leading her to team up with Dr. Stephanie Cave, author of the book What Your Doctor May Not Tell You About Children’s Vaccinations. The two explored the testing and treatment for mercury poisoning in autistic spectrum children for several years in Dr. Amy’s Baton Rouge, Louisiana clinic, successfully treating hundreds of children with autism.

Drs. Holmes and Cave were among the first physicians to use heavy metal chelation to recover autistic children, helping pioneer a new direction in medical detoxification of children based on careful attention to testing and nutrient/mineral supplementation. Their treatment success led to a DAN! Summit where Dr. Holmes was among 26 toxicity experts who met for three days in February of 2001 to create the first consensus paper on mercury detoxification, the Mercury Detoxification Consensus Position Paper in Autism and Related Developmental Disorders.

According to Holmes,

Autism and disorders resembling autism can be caused by a number of disorders, including Fragile X Syndrome, tuberous sclerosis, and phenylketonuria, and by at least one notable chromosomal abnormality, an inverted duplication of a portion of chromosome 15. But for the vast majority of cases of autism today, there is no strictly genetic explanation. As with many chronic disorders, most cases of autism appear to be caused by some genetic predisposition coupled with some early environmental insult…

Bernard, et al, have written an excellent article comparing autism with mercury poisoning. All aspects of both disorders are examined, including symptoms, signs and findings on laboratory tests. The parallels between the two disorders is disturbingly obvious, even to the most casual reader. This, coupled with many case reports of clinical improvement among autistic children upon removal of at least a small part of their whole-body load of mercury, seems to indicate that many cases of autism today are, in fact, cases of mercury poisoning. The early environmental insult, in these cases, is mercury exposure that overwhelmed the body’s attempts at detoxification.


Dr. Holmes is no longer in private practice and Dr. Cave has taken over her patient caseload.


read about Dr. Holmes’ Mercury Chelation Program

sources: Dr. Holmes’ Treatment Program for Autism

see also: Metal-Metabolism and Autism by Amy S. Holmes, MD, Heavy Metal Detoxification and Metallothionein Promotion by Amy S. Holmes, MD,


  • Earthwalker

    Earthwalker is the username that PT founder Julie Genser created for her online interactions so many years ago when first creating Planet Thrive.

    Julie's (Earthwalker's) life was derailed over twenty years ago when she had a very large organic mercury exposure after she naively used a mouth thermometer to measure the temperature of just-boiled milk while making her very first pizza at home. The mercury instantly expanded into a gas form and exploded out the back of the thermometer right into her face. Unaware that mercury was the third most neurotoxic element on Earth, Julie had no idea she had just received a very high dose of a poisonous substance.

    A series of subsequent toxic exposures over the next few years -- to smoke from two fires (including 9/11), toxic mold, lyme disease, and chemical injuries -- caused catastrophic damage to her health. While figuring out how to survive day-to-day, and often minute-to-minute, she created Planet Thrive to help others avoid some of the misdiagnoses and struggles she had experienced.

    She has clawed her way over many health mountains to get to where she is today. She is excited to bring the latest iteration of Planet Thrive to the chronic illness community.

    In 2019, Julie published her very first cookbook e-book called Low Lectin Lunches (+ Dinners, Too!) after discovering how a low lectin, gluten free diet was helping manage her chronic fascia/muscle pain.

2 Comments

  1. Daniela

    Hello,
    My name is Daniela and I am writing from Slovenia. I have a 9 year old son who has been diagnosed with spectrum autistic disorders last year in 2017.
    We would like to do Testing for mercury toxicity and for other heavy metals. How could we do that? I don not know who should I turn to for this testings.

    Thank you very much for your answers.

    Best regards,

    Daniela Kovše

  2. Julie

    Hi Daniela,
    This is the hair test information I share when people ask, but I don’t know if it’s available for those outside of the USA. Please contact them directly to find out. http://home.earthlink.net/~moriam/HOW_TO_hair_test.html

    It seems some of the links on that page are no longer valid. Here is the lab that does hair tests for you if you don’t have a doctor to order it: https://www.directlabs.com/ContactUs/tabid/133/language/en-US/Default.aspx

    Here is the lab that actually does the hair testing but I think you need a doctor to order it: https://www.doctorsdata.com/contact/

    Once you get the test results, you need to interpret using the “Counting Rules” that were developed by the late Andrew Hall Cutler, PhD. http://home.earthlink.net/~moriam/HOW_TO_hair_test.html#counting_rules

    Most children on the spectrum will actually show no or very little heavy metals — that’s because they are non-excretors and keep all the heavy metals in their brain/body. So the Counting Rules will help determine what is going on by looking at the state of mineral transport in the body.

    I hope this is helpful.

    Best wishes, Julie

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