Neurontin and Lyrica are a Death Sentence for New Brain Synapses

by | Oct 29, 2009 | Brain Plasticity News, Fibromyalgia News, NEWS | 3 comments


Lyricasource: wellnessresources.com

Byron J. Richards, CCN reported earlier this month that the popular Fibromyalgia drug Lyrica and its former less potent version Neurontin have both been shown to “block the formation of new brain synapses, drastically reducing the potential for rejuvenating brain plasticity.”

Neurontin was originally produced for epilepsy but was illegally marketed for off-label use by pharmaceutical company Warner-Lambert, the former owner of the drug, who was later fined 430 million dollars.

Lyrica is owned by pharmaceutical giant Pfizer, and was approved by the FDA for pain management including the treatment of fibromyalgia. It, too, was illegally marketed for off-label use and Pfizer lost a $2.3 billion settlement.

Richards writes:

Even though the marketing of these drugs has been heavily fined, they continue to rack up billions in sales from the off-label uses. Doctors use them for all manner of nerve issues because they are good at suppressing symptoms. However, such uses can no longer be justified because the actual mechanism of the drugs is finally understood and they are creating a significant long-term reduction in nerve health.

The researchers in the above study try to downplay the serious nature of the drugs by saying “adult neurons don’t form many new synapses.” That is simply not true. The new science is showing that brain health during aging relies on the formation of new synapses. Even these researchers managed to question the common use of these medications in pregnant women. How is a fetus supposed to make new nerve cells when the mother is taking a drug that blocks them?

These are the kind of situations the FDA should be all over. As usual, the FDA is sitting around pondering a suicide warning for Lyrica while its off-label uses include bi-polar disorder and migraine headaches. The FDA is likely to twiddle its thumbs for the next decade on the brain damage issue. Consumer beware.

Recently here at Planet Thrive, we’ve been publishing articles on the use of brain plasticity to help ameliorate the symptoms of fibromyalgia. What a pity that those who are turning to pharmaceuticals to manage their pain might be reducing their chances for a non-invasive lasting remedy in the process. read the full article

Author

  • Julie Genser, founder of Planet Thrive

    Earthwalker is the username that PT founder Julie Genser created for her online interactions so many years ago when first creating Planet Thrive.

    Julie's (Earthwalker's) life was derailed over twenty years ago when she had a very large organic mercury exposure after she naively used a mouth thermometer to measure the temperature of just-boiled milk while making her very first pizza at home. The mercury instantly expanded into a gas form and exploded out the back of the thermometer right into her face. Unaware that mercury was the third most neurotoxic element on Earth, Julie had no idea she had just received a very high dose of a poisonous substance.

    A series of subsequent toxic exposures over the next few years -- to smoke from two fires (including 9/11), toxic mold, lyme disease, and chemical injuries -- caused catastrophic damage to her health. While figuring out how to survive day-to-day, and often minute-to-minute, she created Planet Thrive to help others avoid some of the misdiagnoses and struggles she had experienced.

    She has clawed her way over many health mountains to get to where she is today. She is excited to bring the latest iteration of Planet Thrive to the chronic illness community.

    In 2019, Julie published her very first cookbook e-book called Low Lectin Lunches (+ Dinners, Too!) after discovering how a low lectin, gluten free diet was helping manage her chronic fascia/muscle pain.

    View all posts

3 Comments

  1. Brain Training Advocate

    This is unbelievable. How on earth can these companies get away with this? Thanks for the report.

    Martin

  2. earthwalker

    It is unbelievable but it is the truth in our country. Our whole country is based on a structure that supports drug companies in doing this. Companies are not required to do extensive long-term safety studies, or if they do, results are allowed to be biased, companies do not have to disclose full ingredients, and are given tax incentives and subsidies to help them poison our land and citizens.

    At least that’s the view from where I sit, poisoned from chemicals and now a virtual prisoner in my home. Thanks to the pervasive lack of regulation on toxic chemicals in our country.

  3. Jason Aaron Childs

    I love neurontin. It always pulls me through when I run out of my prescription medication, Norco. It also helps keep me from going through the nasty drug withdrawal symptoms. It is basically a miracle medication to me. Also, stating the obvious, it does help with the pain.

Submit a Comment

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

You May Also Like…

empowering the environmental illness community