Dear Stephen,
I’ve read Healing Lyme and it’s a good resource. I would like to know whether you have any experience in having patients use your core protocol along with antibiotics long term. Are there any contraindications? Is there any evidence to suggest that your core protocol SHOULD NOT be used with antibiotic treatment (i.e., could the herbs lessen the effect, etc.)?

Stephen’s response:
Thanks. As to long term antibiotics (abx), many people are using the core protocol with abx long term and as far as I know there have been no problems. From what I have heard and from what the literature shows the abx should prove more effective if used with the protocol.
This is for two reasons. The first is that the better the immune system, the better and more efficiently abx work. The herbs in the protocol do help raise immune function.
The second reason is that knotweed is a good synergist for pharmaceuticals; that is, studies have found that even with antibiotic resistant organisms that have not responded to pharmaceuticals, if the pharmaceuticals are retaken along with the knotweed they suddenly become effective. All this is enhanced even more if a collagen support protocol is also being followed.

This protocol was incredible. After only a few weeks most of my symptoms were gone. After six months all my symptoms were gone… it has given me my life back.

– Amazon review by Joseph

Please note:

Stephen Buhner is no longer living and this Q + A column on Planet Thrive is closed to new questions. It will be kept on our website so readers can access vital information in the archives, communicate with each other in the comments section, and find herbs, books + lyme adjuncts in our directory. If you want to read more of Stephen’s writings, please see his website at:

You May Also Like …

Natural solutions for PMS

Natural solutions for PMS

Dear Susun, Is there something natural that would help with severe pre-menstrual syndrome (PMS)? I’m completely done with trying antidepressants. But I still suffer and could really use some help.

read more


Dear Susun, Have you ever worked with adhesions? I have them all throughout my abdominal/pelvic area, esophagus, diaphragm, ribs, and lungs.

read more


empowering the environmental illness community